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KMID : 0363320190400030409
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Journal of Korean Oriental Internal Medicine
2019 Volume.40 No. 3 p.409 ~ p.424
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Systematic Review of Korean Medicine for the Treatment of Sixth Cranial Nerve Palsy
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Won Seo-Young
Kim Min-Ji
Cha Ji-Yun
Jung Eun-Sun
Cho Hyun-Kyoung
Yoo Ho-Rhyong
Seol In-Chan
Kim Yoon-Sik
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Abstract
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Objectives: This research aimed to confirm the efficacy of oriental medicine in sixth cranial nerve palsy and to evaluate the quality of the studies.
Methods: Using the medical subject heading (MeSH) keywords “abducens nerve palsy”, “abducens nerve paralysis”, “sixth nerve palsy”, “herbal medicine”, “Chinese medicine”, “oriental medicine” and “acupuncture”, we collected the research papers through an electronic database search in Oriental Medicine Advanced Searching Integrated System (OASIS), National Discovery for Science Leaders (NDSL), PubMed, Cochran Library, and China National Knowledge Infrastructure (CNKI).
Results: A total of 136 papers were searched from the databases. Among these, 15 case reports and 8 randomized controlled trials (RCTs) met our criteria. 17 articles were found on the use of acupuncture as the main intervention, 11 on the use of herbal medicine as the main intervention, and 9 on the use of electroacupuncture as the main intervention. The frequently used acupoints were LI4, EX-HN5, GB1, BL2, TE23, LR3, BL1, ST2, GB20, and ST36. All 23 studies confirmed the efficacy of Korean medicine. According to the assessment using the risk of bias, the overall quality of the RCTs was low.
Conclusions: Twenty-three papers suggested that Korean medicine treatment for abducens nerve palsy was effective in many cases. Analyzing the potential bias was difficult.
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KEYWORD
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abducens nerve palsy, herbal medicine, acupuncture, electroacupuncture
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